Natural Science Division Coordinator
Reinhart Center 225
- B.S. in Biology, Ball State University, Muncie, Indiana, 1986
- M.S. in Biology, Ball State University, Muncie, Indiana, 1989
- Ph.D. in Immunology, Montana State University, Bozeman, 1997
- Cancer Biology
- Cell and Molecular Biology
- Ecology of Belize
- Human Biology
- Potential Immunosuppressive characteristics of ruthenium compounds
- Tissue transplantation has saved many lives. Unfortunately, in some cases, patients require long-term immunosuppression to prevent rejection of the transplanted tissue. There are many immunosuppressive drugs that are currently used to thwart rejection. However, as with any treatment, scientists are continually looking for new and improved treatment possibilities. Recent studies have demonstrated that ruthenium compounds possess immunosuppressive qualities with reduced side effects. In a collaborative effort between Mike Collins, Ph.D., and myself, we are studying the potential immunosuppressive characteristics of ruthenium compounds. We are interested in determining if the redox properties of various ruthenium compounds will have varying effects on immunosuppression. Specifically, we are testing the impact of ruthenium on T cell production of IL-2.
- Bovine Gamma-delta T cell surface markers
- My students and I are looking at characterizing bovine Gamma-delta T cell surface markers. Gamma-delta T cells are a subset of T cells that appear to possess unique functions. In an effort to understand these cells, we are interested in identifying and characterizing cell surface markers that are unique to these cells. Specifically, several Gamma-delta specific markers are known and we are interested in determining their molecular characteristics and defining possible functions to further elucidate their role in immune systems.